Comparative Evaluation of Bovine-Derived Hydroxyapatite and Commercial Hydroxyapatite for Potential Hard-Tissue Bioceramic Applications
DOI:
https://doi.org/10.55544/sjmars.5.5.9Keywords:
Bovine bone, Bioceramic, Compressive strength, HydroxyapatiteAbstract
Hydroxyapatite (HA) derived from biological waste remains an attractive calcium-phosphate bioceramic, owing to its chemical similarity to the mineral phase of human bone and its potential use in hard-tissue repair. The bovine-bone-derived HA has been widely reported, however, a comparative assessment of thermally treated bovine-derived HA to commercial HA is provided in the present study with emphasis on particle size, phase composition, functional groups, morphology and elemental features for preliminary bioceramic screening. The femur bone of the cow was cleaned, defatted, ground, dried and thermally treated with two-step heating to eliminate organic components and to promote HA crystallization. The obtained powder was characterized using particle size analysis, X-ray diffraction (XRD), Fourier-transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM) and energy-dispersive X-ray spectroscopy (EDX). The bovine-derived powder was characterized by nanoscale particle.
References
[1] T. Romasco, M. Tumedei, F. Inchingolo, P. Pignatelli, L. Montesani, G. Iezzi, M. Petrini, A. Piattelli, and N. Di Pietro, “A narrative review on the effectiveness of bone regeneration procedures with OsteoBiol® collagenated porcine grafts: the translational research experience over 20 years,” Journal of Functional Biomaterials, vol. 13, no. 3, pp. 121, 2022.
[2] S. Wei, J.-X. Ma, L. Xu, X.-S. Gu, and X.-L. Ma, “Biodegradable materials for bone defect repair,” Military medical research, vol. 7, no. 1, pp. 54, 2020.
[3] H. Lin, X. Wang, M. Huang, Z. Li, Z. Shen, J. Feng, H. Chen, J. Wu, J. Gao, and Z. Wen, “Research hotspots and trends of bone defects based on Web of Science: a bibliometric analysis,” Journal of orthopaedic surgery and research, vol. 15, no. 1, pp. 463, 2020.
[4] A. C. Guastaldi, and A. H. Aparecida, “Calcium phosphates of biological interest: Importance as biomaterials, properties and methods for coatings obtaining,” Química Nova, vol. 33, pp. 1352-1358, 2010.
[5] N. Eliaz, and N. Metoki, “Calcium phosphate bioceramics: a review of their history, structure, properties, coating technologies and biomedical applications,” Materials, vol. 10, no. 4, pp. 334, 2017.
[6] K. S. Naik, "Advanced bioceramics," Advances in Biological Science Research, pp. 411-417: Elsevier, 2019.
[7] L. L. Hench, Introduction to Bioceramics, An: World Scientific Publishing Company, 2013.
[8] K. Shanmugam, and R. Sahadevan, “Bioceramics—An introductory overview,” Fundamental biomaterials: ceramics, pp. 1-46, 2018.
[9] J. Neugebauer, T. R. Schoenbaum, J. Pi-Anfruns, M. Yang, B. Lander, M. B. Blatz, and J. P. Fiorellini, “Ceramic Dental Implants: A Systematic Review and Meta-analysis,” International Journal of Oral & Maxillofacial Implants, vol. 38, 2023.
[10] J. Malekani, B. Schmutz, Y. Gu, M. Schuetz, and P. Yarlagadda, “Orthopedic bone plates: Evolution in Structure, Implementation technique and biomaterial,” GSTF Journal of Engineering Technology (JET), vol. 1, no. 1, pp. 135, 2012.
[11] N. A. Barakat, M. S. Khil, A. Omran, F. A. Sheikh, and H. Y. Kim, “Extraction of pure natural hydroxyapatite from the bovine bones bio waste by three different methods,” Journal of materials processing technology, vol. 209, no. 7, pp. 3408-3415, 2009.
[12] N. Ramesh, S. C. Moratti, and G. J. Dias, “Hydroxyapatite–polymer biocomposites for bone regeneration: A review of current trends,” Journal of Biomedical Materials Research Part B: Applied Biomaterials, vol. 106, no. 5, pp. 2046-2057, 2018.
[13] C. Guzman Vazquez, C. Piña Barba, and N. Munguia, “Stoichiometric hydroxyapatite obtained by precipitation and sol gel processes,” Revista mexicana de fisica, vol. 51, no. 3, pp. 284-293, 2005.
[14] K. Thunsiri, S. Pitjamit, P. Pothacharoen, D. Pruksakorn, W. Nakkiew, and W. Wattanutchariya, “The 3D-printed bilayer’s bioactive-biomaterials scaffold for full-thickness articular cartilage defects treatment,” Materials, vol. 13, no. 15, pp. 3417, 2020.
[15] D. N. Ungureanu, “INVESTIGATIONS REGARDING STRUCTURAL CHARACTERISTICS OF SOME CERAMIC POWDERS HEAT-TREATED AT LOW TEMPERATURES,” Valahia University of Targoviste, vol. 2, pp. 83, 2002.
[16] M. Ferraz, F. Monteiro, and C. Manuel, “Hydroxyapatite nanoparticles: a review of preparation methodologies,” Journal of Applied Biomaterials and Biomechanics, vol. 2, no. 2, pp. 74-80, 2004.
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